Thursday April 16, 2015

08:00 - 08:30 Keynote | Keynote Lecture 1
Moderator: L. Scott Levin, United States

Presentation Supported by:  Kleinert Kutz Care Center

CHA2

 

BRB Auditorium
From Autologous to Allologous in Vascularized Composite Allotransplantation (VCA) (Video of Presentation Available)
Fu-Chan Wei
Chang Gung Memorial Hospital, Taiwan
08:30 - 08:45 Plenary | 1- Immunosuppression Management: lessons learned from solid organ transplants
Moderators: L. Scott Levin, United States; Abraham Shaked, United States
BRB Auditorium
Immunosuppression Management: lessons learned from solid organ transplants (Video of Presentation Available)
Abraham Shaked
Director, Penn Transplant Institute, Philadelphia, United States
08:45 - 09:45 Panel Discussion | VCA in Different Countries
Moderators: Linda C. Cendales, United States; Fu-Chan Wei, Taiwan
BRB Auditorium
Current Problems with VCA Programs in Developing Countries and Potential Solutions
Eric Santamaria
Professor in Reconstructive Microsurgery, Division of Plastic and Reconstructive Surgery, Hospital General Dr. Manuel Gea González, Mexico city, Mexico
Clinical Outcomes in VCA in Western Countries
Emmanuel Morelon
director of VCA medical program, head of renal and pancreas transplant program, Transplantation, Hospices Civils de Lyon, Lyon, France
Panel Discussions

09:45 - 10:15 | Coffee Break

Supported by:  Center for Human Appearance

BRB Foyer
10:15 - 12:30 Speed Update | Speed Update on Science - Selected Research Labs Around the World Working on VCA
Moderators: Gerald Brandacher, United States; Christina Kaufman, United States
BRB Auditorium
British Lab
Fadi Issa
Clinical Lecturer, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom
University of Maryland
Rolf N Barth
Associate Professor of Surgery, Department of Surgery, University of Maryland School of Medicine, Baltimore, United States
Brigham and Women's Hospital
Ericka M Bueno
Scientific Director, Plastic Surgery, Brigham and Women's Hospital, Boston, United States
The Development of VCA - Research Center in Taiwan (Video of Presentation Available)
Yur-Ren Kuo
Chairman and professor, department of surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohisung, Taiwan
Duke University
Linda C. Cendales
Associate Professor of Surgery, Director VCA Program,, Department of Surgery, Duke University, Durham, United States
Facial Allotransplantation: Experiences of Xijing Hospital (Video of Presentation Available)
Yingjun Su
Associate Professor, Department of Plastic and Reconstructive Surgery, Xijing Hospital, Xi'an, People's Republic of China
UCLA
Jerzy W. Kupiec-Weglinski
Professor, Surgery/Liver Transplantation, UCLA, Los Angeles, United States
John Hopkins (Video of Presentation Available)
Gerald Brandacher
Scientific Director, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
From Laboratory to Clinical VCA Transplantation
Maria Siemionow
Professor, Department of Orthopaedics, University of Illinois at Chicago, Chicago, United States
Face Transplantation - Cleveland Clinic Update
Maria Siemionow
Professor, Department of Orthopaedics, University of Illinois at Chicago, Chicago, United States
Austria Lab
Stefan Schneeberger
Head, Transplant Surgery, Dept. of Visceral Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria
Louisville (Video of Presentation Available)
Christina Kaufman
Executive Director, Christine M Kleinert Institute for Hand and Microsurgery, Louisville, United States
Upenn and Overview
Wayne W. Hancock
Children's Hospital of Philadelphia, Philadelphia, United States
12:30 - 13:15 | Lunch Break
BRB Foyer
13:15 - 14:30 Oral Communciations | Abstract Session 1
Moderators: Laurent Lantieri, France; Stephen J. Kovach III, United States
BRB Auditorium
Capillary vessel thrombosis in the skin of human Vascularized Composite Tissue Allografts: a new pathologic finding of (severe) rejection? (Video of Presentation Available)
Jean Kanitakis MD
Hospital Practitioner, Dept. of Dermatology, Ed. Herriot Hospital Group (Pav; R), Lyon cedex 03, France
A Scoring Tool for Subject Screening in Facial Allotransplantation (Video of Presentation Available)
Vijay Gorantla MD, PhD, FRCS
Associate Professor of Surgery | Administrative Medical Director , Reconstructive Transplantation | Department of Plastic Surgery , University of Pittsburgh Medical Center, Pittsburgh, United States
Standardized allocation criteria for vascularized composite allografts to optimize donor-recipient matching
Néha Datta
Resident Physician, Department of Surgery, University of California Los Angeles, Los Angeles, United States
The International Registry on Hand and Composite Tissue Transplantation (IRHCTT) (Video of Presentation Available)
Palmina Petruzzo
Professor of Vascular Surgery, Department of Transplantation, Hopital Edouard Herriot, Lyon, France
Post transplantation high-dose cyclophosphamide treatment to promote immune tolerance after reconstructive transplantation in a mouse model. (Video of Presentation Available)
Georg J Furtmüller
Postdoctoral Research Fellow, Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
Comparative Efficacy of two cell-based Therapies for Immunomodulation in Vascularized Composite Allotransplantation
Jan A Plock
Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland
Long-term high-dose tacrolimus monotherapy is associated with significant infectious complications in a large animal vascularized composite allotransplantation model
Edward W Swanson
Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Baltimore, United States
The Role of Skin-Specific Immunobiology and Major Histocompatibility Complex Sharing in Vascularized Composite Allograft Tolerance (Video of Presentation Available)
David A. Leonard
Research Fellow, Vascularized Composite Allotransplantation Lab, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, United States
14:30 - 15:30 Plenary | 2- Organ Procurement
Moderators: Richard D. Hasz, United States; Stacey L. Doll, United States
BRB Auditorium
Organ Procurement in USA (Video of Presentation Available)
Howard M. Nathan
President & CEO, Gift of Life Donor Program, Philadelphia, United States
Organ Procurement in Europe
Karim Laouabdia-Sellami
Deputy general director, Medical and Scientific department, Agence de la biomédecine, Saint-Denis La Plaine Cedex, France
Australia and New Zealand VCA regulation
Timothy Bennett
Director of Plastic Surgery, Hand, Plastic & Reconstructive Surgery, St. Vincent's Public Hospital, Fitzroy, Australia
15:30 - 15:45 | Coffee Break
BRB Foyer
15:45 - 18:15 Mini-Oral | Mini-Oral Session
Moderators: Jaimie T Shores, United States; Kodi Azari, United States
BRB Auditorium
Normothermic preservation of the rat hind limb with artificial oxygen-carrying hemoglobin vesicles (Video of Presentation Available)
Jun Araki
Plastic surgery, University of Tokyo, Tokyo, Japan
International collaboration research of anorectal transplantation (Video of Presentation Available)
Jun Araki
Plastic surgery, University of Tokyo, Tokyo, Japan
Rat Forelimb Allotransplantation: A Novel Microsurgical Model for Optimized Functional Assessment after Reconstructive Transplantation (Video of Presentation Available)
Joshua D. Budihardjo
Research Fellow, Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, United States
A novel method of osteosynthesis in distal forearm transplantation using an ulnar-shortening osteotomy system for simultaneous both bone fixation (Video of Presentation Available)
Shaun D Mendenhall
Plastic Surgery Resident, Institute for Plastic Surgery, Southern Illinois University School of Medicine, Springfield, United States
Donor-Recipient Chimeric Cell - A New Bridging Therapy Against Acute Radiation Syndrome
Joanna Cwykiel
Research Specialist, Othopaedics, University of Illinois at Chicago, Chicago, United States
Assessment of Regenerative Potential of Human Epineural Sheath Conduit Supported by Human Mesenchymal Stem Cells Therapy
Joanna Cwykiel
Research Specialist, Othopaedics, University of Illinois at Chicago, Chicago, United States
The impact and mechanisms of antibody-mediated rejection in vascularized composite allotransplantation (Video of Presentation Available)
Devin T Miller
Medical Student, Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, United States
In Vitro Characterization of Human Hematopoietic Chimeric Cells – a Novel Tolerance Inducing Strategy in Transplantation
Maria Siemionow
Professor, Department of Orthopaedics, University of Illinois at Chicago, Chicago, United States
Phenotype Characterization, Migratory Pathways, Engraftment and Safety Evaluation of Human Cord Blood Derived Ex-Vivo Created Di- Chimeric in NOD SCID Mouse Model: A Preliminary Study.
Joanna Cwykiel
Research Specialist, Othopaedics, University of Illinois at Chicago, Chicago, United States
Pathology review of skin biopsies and mononuclear cell infiltrates characterization from a bilateral forearm transplant. What we have treated? (Video of Presentation Available)
Mario Arturo Moran-Romero
Intern, Department of Plastic and Reconstructive Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico city, Mexico
Clinical and Immunological Update of the Innsbruck Hand Transplant Program: Subsequent Kidney Transplantation after a Bilateral Hand Transplant (Video of Presentation Available)
Annemarie Weissenbacher
Surgeon, University Hospital for Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria
Upper Extremity Transplantation: Functional and Immunological Status Two Years Post-Transplant (Video of Presentation Available)
David A. Leonard
Research Fellow, Vascularized Composite Allotransplantation Lab, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, United States
Multi-Digital Allotransplantation for Reconstruction of the Metacarpal Hand (Video of Presentation Available)
Antonio Rampazzo
Staff, Plastic Surgery, Cleveland Clinic, Cleveland, United States
Ultra-high field upper extremity peripheral nerve and non-contrast vascular imaging with 7 Tesla high resolution MRI (Video of Presentation Available)
Shailesh B. Raval
University of Pittsburgh, Pittsburgh, United States
Ultrahigh field (7T) magnetic resonance musculoskeletal imaging in upper extremity allotransplantation - first report in VCA (Video of Presentation Available)
Shailesh B. Raval
University of Pittsburgh, Pittsburgh, United States
Comic for the promotion of donation of vascularized composite allografts in Mexico (Video of Presentation Available)
María Fernanda Ramírez-Berumen
National Institute of Medical Sciences and Nutrition "Salvador Zubirán", Mexico city, Mexico
Automated segmentation analysis of nerve fascicular anatomy using high resolution ultrasound imaging for objective non- invasive assessment of nerve regeneration after VCA (Video of Presentation Available)
Vijay Gorantla MD, PhD, FRCS
Associate Professor of Surgery | Administrative Medical Director , Reconstructive Transplantation | Department of Plastic Surgery , University of Pittsburgh Medical Center, Pittsburgh, United States
Dynamic skeletal changes of an osteomyocutaneous facial allograft five years following transplantation
Bahar Bassiri Gharb
Staff, Plastic Surgery, Cleveland Clinic, Cleveland, United States
Influence of Using a Single Facial Vein as Outflow in Full Face Transplantation: A Three-Dimensional Computed Tomographic Study (Video of Presentation Available)
Andres Rodriguez
Director of Microsurgery. Consultant in Plastic Surgery, Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden
Nerve Transfers in Face Transplantation (Video of Presentation Available)
Andres Rodriguez
Director of Microsurgery. Consultant in Plastic Surgery, Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden
Brief peri-transplant therapy with CD40L, donor splenocyte transfusion (DST) and rapamycin (RPM) causes long-term hindlimb vascularized composite allograft (VCA) survival without a need for maintenance immunosuppression
Wayne W. Hancock
Children's Hospital of Philadelphia, Philadelphia, United States
A Statistical Comparative Assessment Of Face And Hand Transplantation Outcomes To Determine If Either Meet The Standard Of Care Threshold
Warren C Breidenbach
professor plastic surgery, department of surgery, University of Arizona, Tucson, United States
FIRST BILATERAL HAND TRANSPLANTATION IN TURKEY : AN UPDATE OF OUTCOMES
Nîlgün Keçecioglu
tx coordinator, composite tissue center, antalya, Turkey
18:15 - 19:15 | Welcome Reception
BRB 14th Floor
20:00 Congress Dinner | Gala Dinner at the College of Physicians of Philadelphia (Ticket required)

Friday April 17, 2015

08:00 - 09:00 Plenary | 3- Expert Opinion on VCA
Moderators: Emmanuel Morelon, France; Stefan Schneeberger, Austria
BRB Auditorium
Chronic Rejection in Human VCA (Video of Presentation Available)
Jean Kanitakis MD
Hospital Practitioner, Dept. of Dermatology, Ed. Herriot Hospital Group (Pav; R), Lyon cedex 03, France
Impact of Donor-Specific Antibodies and Antibody-Mediated Rejection in VCA and Solid Organ Transplantation (Video of Presentation Available)
Gerald Brandacher
Scientific Director, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
Cell Base Therapies (Video of Presentation Available)
Edward K. Geissler
Professor, Experimental Surgery, University Hospital Regensburg, Regensburg, Germany
09:00 - 09:15 | Keynote Lecture 2
BRB Auditorium
First Successful Penile Transplant In The World (Webcast)
Andre Van der Merwe
Head of the Division of Urology, Department of Surgical Sciences, Stellenbosch University , Stellenbosch, South Africa
09:15 - 09:30 Plenary | Presidential Address
Moderator: Linda C. Cendales, United States
BRB Auditorium
Presidential Address (Video of Presentation Available)
Palmina Petruzzo
Professor of Vascular Surgery, Department of Transplantation, Hopital Edouard Herriot, Lyon, France
09:30 - 10:00 | Coffee Break
Supported by: Kleinert Kutz Care Center
CHA2
BRB Foyer
10:00 - 11:20 Panel Discussion | Indications and Exite Strategies in Upper and Face Transplantations
Moderators: Maria Siemionow, United States; Yur-Ren Kuo, Taiwan
BRB Auditorium
Upper Extremity (Video of Presentation Available)
Vijay Gorantla MD, PhD, FRCS
Associate Professor of Surgery | Administrative Medical Director , Reconstructive Transplantation | Department of Plastic Surgery , University of Pittsburgh Medical Center, Pittsburgh, United States
Upper Extremity
Adam Domanasiewicz
Poland
Upper Extremity
Jaimie T Shores
Clinical Director of Hand and Upper Extremity Transplantation, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
Face
Bohdan Pomahac
Director of Plastic Surgery Transplantation, Plastic Surgery, Brigham and Women's Hospital, Boston, United States
Face (Video of Presentation Available)
Laurent Lantieri
Professor of plastic surgery, Hopital Europeen Georges Pompidou, PARIS, France
Face
Ozlenen Ozkan
Akdeniz University Department of Plastic Surgery, ANTALYA, Turkey
Discussion

11:30 - 12:15 Plenary | 4- Meet the Patients
Moderators: L. Scott Levin, United States; Bohdan Pomahac, United States
BRB Auditorium
12:15 - 13:15 | Lunch Break / IHCTAS Business Meeting (Members only)
BRB Foyer
13:15 - 13:45 | Keynote Lecture 3
Moderators: L. Scott Levin, United States; Christos Coutifaris, United States
BRB Auditorium
Uterine Transplantation (Video of Presentation Available)
Mats Brannstrom
Göteborg, Sweden
13:45 - 15:45 Oral Communciations | Abstract Session 2
Moderators: Linda C. Cendales, United States; Vijay Gorantla MD, PhD, FRCS, United States
BRB Auditorium
Monitoring of arterial vessels in upper extremity transplantation (Video of Presentation Available)
Palmina Petruzzo
Professor of Vascular Surgery, Department of Transplantation, Hopital Edouard Herriot, Lyon, France
Objective metrics of immunosuppression adherence in upper extremity transplantation – the Pittsburgh experience (Video of Presentation Available)
Vijay Gorantla MD, PhD, FRCS
Associate Professor of Surgery | Administrative Medical Director , Reconstructive Transplantation | Department of Plastic Surgery , University of Pittsburgh Medical Center, Pittsburgh, United States
Non-invasive imaging modalities for immune monitoring of vascularized composite allografts in a swine heterotopic hind limb transplantation model. (Video of Presentation Available)
Georg J Furtmüller
Postdoctoral Research Fellow, Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
A New Modality for a New VCA Model: Defining the MLR Based Kinetics of Immune Modulation in Bone Marrow Derived MSCs Using Live Imaging. (Video of Presentation Available)
Denver M. Lough
Resident and Research Fellow, Department of Plastic and Reconstructive Surgery, Johns Hopkins, Baltimore, United States
A Novel Rodent Model to Define the Rejection Process after Penile Transplantation (Video of Presentation Available)
Denver M. Lough
Resident and Research Fellow, Department of Plastic and Reconstructive Surgery, Johns Hopkins, Baltimore, United States
Blood NKT cells may differentiate stable from rejecting recipients in vascularized composite allotransplantation
Emmanuel Morelon
director of VCA medical program, head of renal and pancreas transplant program, Transplantation, Hospices Civils de Lyon, Lyon, France
Autologous adipose-derived stem cell infusion as salvage therapy for relapsing rejection of vascularised composite allotransplantation: a first clinical case report
Emmanuel Morelon
director of VCA medical program, head of renal and pancreas transplant program, Transplantation, Hospices Civils de Lyon, Lyon, France
Novel Site-Specific Immunosuppression Strategies for Vascularized Composite Allotransplantation
Vijay Gorantla MD, PhD, FRCS
Associate Professor of Surgery | Administrative Medical Director , Reconstructive Transplantation | Department of Plastic Surgery , University of Pittsburgh Medical Center, Pittsburgh, United States
Non-cytoreductive immunosuppression prevents rejection of vascularized composite allografts. (Video of Presentation Available)
Byoungchol Oh
Postdoctoral fellow, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
Costimulatory blockade prevents rejection of vascularized composite allografts. (Video of Presentation Available)
Byoungchol Oh
Postdoctoral fellow, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, United States
Use of a clinically relevant T cell depletion strategy (anti-TCR mAb) to promote long-term hindlimb vascularized composite allograft (VCA) survival
Wayne W. Hancock
Children's Hospital of Philadelphia, Philadelphia, United States
Pathogenic heterogeneity of cellular rejection in skin and mucous membrane of face transplant : a series of 7 cases with a long follow-up
Anissa Moktefi
Pathology Department, Henri Mondor Hospital, Créteil, France
Secondery Aesthetic Procedures in Face Transplantation Patients
Seckin Aydin Savas
resident, Akdeniz University Department of Plastic and Reconstructive Surgery, Antalya, Turkey
Assessment of Immunologic, Proangiogenic and Neurogenic Factors of the Human Peripheral Nerve Epineurium for Potential Application in Prevention of Neuroma Formation
Aleksandra Klimczak
Associate professor, Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wroclaw, Poland
A sheep model for revascularised laryngeal allotransplantation: A novel preclinical large animal model for human laryngeal allotransplantation
Sabapathy G.S. Krishnan
Resident Medical Officer , Department of Otolaryngology, Head and Neck Surgery , Royal Adelaide Hospital , Joslin , Australia
15:45 - 16:15 | Coffee Break

Supported by:  Istituto Italiano Di Chirurgia Della Mano

BRB Foyer
16:15 - 17:45 Plenary | 5- Chauvet Session
Moderators: Christian Seulin, France; Elisa Moreno, United States
BRB Auditorium
Managing Ethical Issues in VCA (Webcast) (Video of Presentation Available)
Katrina A. Bramsted
Professor, Clinical Ethicist, Medical School, Bond University, Gold Coast, Australia
Summary of the First Chauvet Workshop
Sheila G Jowsey-Gregoire
Psychiatrist, Dept of Psychiatry, Mayo Clinic, Rochester, United States
Body Image Issues in Face Transplantation (Video of Presentation Available)
David B. Sarwer
Professor of Psychology, Departments of Psychiatry and Surgery , Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States
Psychiatric Issues in Face Transplantation: Boston experience (Video of Presentation Available)
Simon G Talbot
Director of Upper Extremity Transplantation, Division of Plastic Surgery, Brigham and Women's Hospital, Boston, United States
Facial Transplantation: The Cleveland Clinic experience
Kathy L. Coffman
Staff Psychiatrist, Psychiatry, Cleveland Clinic, Cleveland, United States
Psychiatric and Psychological Issues in Face Transplantation: Barcelona experience (Video of Presentation Available)
Sara-Guila Fidel Kinori
clinical psychologist, Psychiatry Unit, Vall d'Hebron University Hospital, Barcelona, Spain
Psychiatric issues in Face Transplantation: Lyon experience (Video of Presentation Available)
Christian Seulin
psychiatrist psychoanalyst, Hopital Edouard Herriot, Lyon, France
17:45 - 18:00 Plenary | Closing Remarks
BRB Auditorium

Saturday April 18, 2015

09:00 - 17:00 Post-Congress | Cadaver Workshop: Arm and Face Transplantation
Penn Human Tissue Laboratory